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This profile ensures continuous GLP-1 receptor activation throughout the dosing interval, eliminating the peak-to-trough variability that can compromise glycemic control with shorter-acting agents
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What the study measured Shah and colleagues used TriNetX, a federated network of United States electronic health records, and compared 617,296 adults with obesity who received GLP-1 receptor agonist therapy against 3,503,102 controls, across records running from 1 January 2016 to 3 December 2025 [1]
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